Home > Products > CD44 & CR3 > Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Diabody)

Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Diabody)  (SCDB-H293)

Recombinant Anti-CD44 x Anti-CR3 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can recruit macrophages to tumor cells. It is designed for the research of Glioblastoma; Squamous cancer therapy.

Specifications
Targets
CD44 & CR3
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
CD44
Host Animal 1
Human
Target 2
CR3
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Glioblastoma; Squamous cancer
Targets
Target 1
CD44
Gene ID
UniProt ID
Alternative Names
CD44; CD44 antigen; ECMRIII; Extracellular matrix receptor III; HCAM; Homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; HUTCH-1; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109
Target 2
CR3
Gene ID
UniProt ID
Alternative Names
C3AR1; complement C3a receptor 1; AZ3B; C3AR; HNFAG09; CR3; Complement receptor type 3; CD11b/CD18; Mac-1; Macrophage antigen 1; αmβ2

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