Home > Products > CD45 & Myosin > Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-Fc-scFv)

Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-Fc-scFv)  (BSTF-122)

Recombinant Anti-CD45 x Anti-Myosin Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD45 scFv is fused to the N-terminus of Fc via a hinge region while another anti-Myosin scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can recruit stem cells to infarcted myocardium. It is designed for the research of Myocardial infarction therapy.

Specifications

Targets
CD45 & Myosin
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD45
Host Animal 1
Mouse
Target 2
Myosin
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Myocardial infarction

Targets

Target 1
CD45
Gene ID
UniProt ID
Alternative Names
PTPRC; CD45; Cluster of differentiation 45; protein tyrosine phosphatase, receptor type C; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
Target 2
Myosin
Alternative Names
Myosin; ATP-dependent motor proteins

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