Recombinant Human Anti-CD55 x Human Anti-CA9 Bispecific Antibody (Diabody-CH3) (BSDBC-H297)

Recombinant Anti-CD55 x Anti-CA9 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CD55 and anti-CA9 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can recruit complements to tumor cells. It is designed for the research of Renal cell cancer (RCC); Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD55 & CA9

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Renal cell cancer (RCC); Solid tumors

Targets

Target 1

CD55

Gene ID

1604

UniProt ID

P08174

Alternative Names

CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CR; TC; DAF; CROM; complement decay-accelerating factor; CD55 antigen

Target 2

CA9

Gene ID

768

UniProt ID

Q16790

Alternative Names

CA9; carbonic anhydrase 9; RCC-associated antigen G250; G250; CA-IX; carbonic anhydrase IX; MN; CAH9

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD55 x Human Anti-CA9 Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-H297)

Specifications

Targets

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