Home > Products > CD55 & CA9 > Recombinant Anti-CD55 x Anti-CA9 Bispecific Antibody (F(ab')2-scFv2)

Recombinant Anti-CD55 x Anti-CA9 Bispecific Antibody (F(ab')2-scFv2)  (BABFV-123)

Recombinant Anti-CD55 x Anti-CA9 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CD55 specificity is fused to the C terminus of the anti-CA9 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can recruit complements to tumor cells. It is designed for the research of Renal cell cancer (RCC); Solid tumors therapy.

Specifications

Targets
CD55 & CA9
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
CD55
Host Animal 1
Mouse
Target 2
CA9
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Renal cell cancer (RCC); Solid tumors

Targets

Target 1
CD55
Gene ID
UniProt ID
Alternative Names
CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CR; TC; DAF; CROM; complement decay-accelerating factor; CD55 antigen
Target 2
CA9
Gene ID
UniProt ID
Alternative Names
CA9; carbonic anhydrase 9; RCC-associated antigen G250; G250; CA-IX; carbonic anhydrase IX; MN; CAH9

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