Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (Minibody) (MiniB-124)

Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD55 scFv fused to N-terminus of Knob-CH3 domain and the anti-HLA-A scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can recruit complements to tumor cells. It is designed for the research of Renal cell cancer (RCC); Solid tumors therapy.

Datasheet

Specifications

Targets

CD55 & HLA-A

Type

Minibody

Species Reactivity

Human

Target 1

CD55

Host Animal 1

Mouse

Target 2

HLA-A

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

Renal cell cancer (RCC); Solid tumors

Targets

Target 1

CD55

Gene ID

1604

UniProt ID

P08174

Alternative Names

CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CR; TC; DAF; CROM; complement decay-accelerating factor; CD55 antigen

Target 2

HLA-A

Gene ID

3105

UniProt ID

P30443

Alternative Names

HLA-A; major histocompatibility complex, class I, A; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain

Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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INQUIRY

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USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
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UK
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Tel: 44-207-097-1828
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