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Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (scFv-CH3) (CAT#: BSFC-124)
Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD55 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-HLA-A scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can recruit complements to tumor cells. It is designed for the research of Renal cell cancer (RCC); Solid tumors therapy.
HLA-A; major histocompatibility complex, class I, A; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain
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