Name: Recombinant Human Anti-CD55 x Human Anti-HLA-A Bispecific Antibody (scFv-Fc-scFv)
SKU: BSTF-H298
Rating: 5 (1 reviews)

Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD55 scFv is fused to the N-terminus of Fc via a hinge region while another anti-HLA-A scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can recruit complements to tumor cells. It is designed for the research of Renal cell cancer (RCC); Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD55 & HLA-A

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Renal cell cancer (RCC); Solid tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD55

Gene ID

1604

UniProt ID

P08174

Alternative Names

CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CR; TC; DAF; CROM; complement decay-accelerating factor; CD55 antigen

Target 2

HLA-A

Gene ID

3105

UniProt ID

P30443

Alternative Names

HLA-A; major histocompatibility complex, class I, A; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD55 x Human Anti-HLA-A Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-H298)

Specifications

Targets

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