Home > Products > CD55 & HLA-A > Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (scFv-IgG)

Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (scFv-IgG)  (BSSG-H298)

Recombinant Anti-CD55 x Anti-HLA-A Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD55 antibody variable domain are respectively connected to the N terminus of the anti-HLA-A IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can recruit complements to tumor cells. It is designed for the research of Renal cell cancer (RCC); Solid tumors therapy.

Specifications
Targets
CD55 & HLA-A
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD55
Host Animal 1
Human
Target 2
HLA-A
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Renal cell cancer (RCC); Solid tumors
Targets
Target 1
CD55
Gene ID
UniProt ID
Alternative Names
CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CR; TC; DAF; CROM; complement decay-accelerating factor; CD55 antigen
Target 2
HLA-A
Gene ID
UniProt ID
Alternative Names
HLA-A; major histocompatibility complex, class I, A; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain

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