Home > Products > CD64 & EGFR > Recombinant Human Anti-CD64 x Anti-EGFR Bispecific Antibody (Tandem scFv)

Recombinant Human Anti-CD64 x Anti-EGFR Bispecific Antibody (Tandem scFv)  (BSFV-H297)

Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Tandem scFv) is designed to be expressed as a scFv from an anti-CD64 antibody variable domains fused with a scFv from an anti-EGFR antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors therapy.

Specifications

Targets
CD64 & EGFR
Type
Tandem scFv
Species Reactivity
Human
Target 1
CD64
Host Animal 1
Human
Target 2
EGFR
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC)Renal cell cancer (RCC) Solid tumors

Targets

Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
EGFR
Gene ID
UniProt ID
Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

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