Name: Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (F(ab')2-scFv2)
SKU: BABFV-126
Rating: 5 (1 reviews)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CD64 specificity is fused to the C terminus of the anti-GD2 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD64 & GD2

Type

F(ab')2-scFv2

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-126)

Specifications

Targets

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