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Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Fab-Fv) (CAT#: FABFV-126)
Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-CD64 antibody are fused with the VL and VH domains of an anti-GD2 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
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