Home > Products > CD64 & GD2 > Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Fv-IgG)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Fv-IgG)  (BSDG-126)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-CD64 IgG with similar domains from an anti-GD2 antibody via short peptide linkers, or vice versa. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Specifications
Targets
CD64 & GD2
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD64
Host Animal 1
Mouse
Target 2
GD2
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors
Targets
Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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