Home > Products > CD64 & GD2 > Recombinant Human Anti-CD64 x Human Anti-GD2 Bispecific Antibody (Minibody)

Recombinant Human Anti-CD64 x Human Anti-GD2 Bispecific Antibody (Minibody)  (MiniB-H300)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD64 scFv fused to N-terminus of Knob-CH3 domain and the anti-GD2 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Specifications
Targets
CD64 & GD2
Type
Minibody
Species Reactivity
Human
Target 1
CD64
Host Animal 1
Human
Target 2
GD2
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors
Targets
Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

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