Home > Products > CD64 & GD2 > Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (scDiabody-CH3)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (scDiabody-CH3)  (SCDBC-126)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD64/anti-GD2 diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Specifications
Targets
CD64 & GD2
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD64
Host Animal 1
Mouse
Target 2
GD2
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors
Targets
Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

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