Name: Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (scFv-CH3)
SKU: BSFC-126
Rating: 5 (1 reviews)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD64 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-GD2 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD64 & GD2

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-126)

Specifications

Targets

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