Name: Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (sdAb-Fc-sdAb)
SKU: HCAB-037
Rating: 5 (1 reviews)

Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (sdAb-Fc-sdAb, Tetravalent Heavy Chain-only Antibody, Tetravalent HCAb) is symmetric protein with two pairs of single domain antibodies (sdAb), from anti-CD64 and anti-GD2 antibodies, fused to the N-terminus and C-terminus of the Fc separately. This BsAb is bispecific, tetravelant, 2+2 antigen-binding valency. It can retarget neutrophils cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD64 & GD2

Type

sdAb-Fc-sdAb

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Host Animal 1

llama

Host Animal 2

llama

Targets

Target 1

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Target 2

GD2

Gene ID

155971

UniProt ID

Q0H5Z9

Alternative Names

ENV; gp160; Envelope glycoprotein 120; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; human immunodeficiency virus type 1; human immunodeficiency virus type 1 gp120; human immunodeficiency virus type 1 glycoprotein 120; gp41; GP41; glycoprotein 41

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (sdAb-Fc-sdAb) (CAT#: HCAB-037)

Specifications

Targets

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