Name: Recombinant Anti-CD64 x Anti-HER2 Bispecific Antibody (sdAb-IgG)
SKU: BSSG-394
Rating: 5 (1 reviews)

Recombinant Anti-CD64 x Anti-HER2 Bispecific Antibody (sdAb-IgG) is formed by an IgG and two single domains antibodies (sdAbs). The sdAbs from an anti-HER2 antibody variable domain are respectively connected to the N terminus of the anti-CD64 IgG heavy chains or light chains to form sdAb-(H)IgG or sdAb-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD64 & HER2

Type

sdAb-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors

Host Animal 1

Mouse

Host Animal 2

llama

Targets

Target 1

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Target 2

HER2

Gene ID

2064

UniProt ID

P04626

Alternative Names

ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD64 x Anti-HER2 Bispecific Antibody (sdAb-IgG) (CAT#: BSSG-394)

Specifications

Targets

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