Home > Products > CD64 & HIV-1 gp41 > Recombinant Anti-CD64 x Anti-HIV-1 gp41 Bispecific Antibody (Fab-IgG)

Recombinant Anti-CD64 x Anti-HIV-1 gp41 Bispecific Antibody (Fab-IgG)  (FABIG-127)

Recombinant Anti-CD64 x Anti-HIV-1 gp41 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can retarget neutrophils cells to HIV-1 infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.

Specifications

Targets
CD64 & HIV-1 gp41
Type
Fab-IgG
Species Reactivity
Human
Target 1
CD64
Host Animal 1
Mouse
Target 2
HIV-1 gp41
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS

Targets

Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
HIV-1 gp41
Gene ID
UniProt ID
Alternative Names
ENV; gp160; Envelope glycoprotein 120; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; human immunodeficiency virus type 1; human immunodeficiency virus type 1 gp120; human immunodeficiency virus type 1 glycoprotein 120; gp41; GP41; glycoprotein 41

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