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Recombinant Anti-CD64 x Anti-HIV-1 gp41 Bispecific Antibody (scFv-Fc)  (CAT#: BSCFV-127)

Recombinant Anti-CD64 x Anti-HIV-1 gp41 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CD64 specificity or anti-HIV-1 gp41 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of HIV-1 infection, AIDS therapy.
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Specifications

Targets
CD64 & HIV-1 gp41
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS

Targets

Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
HIV-1 gp41
Gene ID
UniProt ID
Alternative Names
ENV; gp160; Envelope glycoprotein 120; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; human immunodeficiency virus type 1; human immunodeficiency virus type 1 gp120; human immunodeficiency virus type 1 glycoprotein 120; gp41; GP41; glycoprotein 41
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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