Home > Products > CD64 & malaria antigen > Recombinant Anti-CD64 x Anti-malaria antigen Bispecific Antibody (Fab-scFv-Fc)

Recombinant Anti-CD64 x Anti-malaria antigen Bispecific Antibody (Fab-scFv-Fc)  (FABVC-H303)

Recombinant Anti-CD64 x Anti-malaria antigen Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD64 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-malaria antigen to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of Malaria therapy.

Specifications
Targets
CD64 & malaria antigen
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
CD64
Host Animal 1
Human
Target 2
malaria antigen
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Malaria
Targets
Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
malaria antigen
Alternative Names
malaria antigen; parasitic protozoans

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