Recombinant Human Anti-CD64 x Human Anti-malaria antigen Bispecific Antibody (scFv4-Ig) (FVTIG-H303)

Recombinant Anti-CD64 x Anti-malaria antigen Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CD64 scFv is fused to the CH1 domain of a heavy chain and another anti-malaria antigen scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of Malaria therapy.

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Specifications

Targets

CD64 & malaria antigen

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Malaria

Targets

Target 1

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Target 2

malaria antigen

Alternative Names

malaria antigen; parasitic protozoans

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD64 x Human Anti-malaria antigen Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-H303)

Specifications

Targets

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