Recombinant Human Anti-CD8 x Human Anti-PSCA Bispecific Antibody (Fab-scFv-Fc) (FABVC-H304)

Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD8 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-PSCA to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget T cells to tumor cells. It is designed for the research of Prostate cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD8 & PSCA

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Prostate cancer

Targets

Target 1

CD8

Gene ID

925

UniProt ID

P01732

Alternative Names

CD8A; CD8a molecule; Cluster of differentiation 8; CD8; MAL; p32; Leu2

Target 2

PSCA

Gene ID

8000

UniProt ID

D3DWI6

Alternative Names

PSCA; prostate stem cell antigen; PRO232

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD8 x Human Anti-PSCA Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-H304)

Specifications

Targets

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