Home > Products > CD8 & PSCA > Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (scFv-CH3)

Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (scFv-CH3)  (BSFC-H304)

Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD8 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-PSCA scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget T cells to tumor cells. It is designed for the research of Prostate cancer therapy.

Specifications
Targets
CD8 & PSCA
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD8
Host Animal 1
Mouse
Target 2
PSCA
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Prostate cancer
Targets
Target 1
CD8
Gene ID
UniProt ID
Alternative Names
CD8A; CD8a molecule; Cluster of differentiation 8; CD8; MAL; p32; Leu2
Target 2
PSCA
Gene ID
UniProt ID
Alternative Names
PSCA; prostate stem cell antigen; PRO232

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