Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (scFv-Fc-scFv) (BSTF-131)

Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD8 scFv is fused to the N-terminus of Fc via a hinge region while another anti-PSCA scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget T cells to tumor cells. It is designed for the research of Prostate cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD8 & PSCA

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Prostate cancer

Targets

Target 1

CD8

Gene ID

925

UniProt ID

P01732

Alternative Names

CD8A; CD8a molecule; Cluster of differentiation 8; CD8; MAL; p32; Leu2

Target 2

PSCA

Gene ID

8000

UniProt ID

D3DWI6

Alternative Names

PSCA; prostate stem cell antigen; PRO232

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-131)

Specifications

Targets

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