Home > Products > CD8 & PSCA > Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (Tandem scFv-Fc)

Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-131)

Recombinant Anti-CD8 x Anti-PSCA Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-CD8/PSCA tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of Prostate cancer therapy.

Specifications

Targets
CD8 & PSCA
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD8
Host Animal 1
Mouse
Target 2
PSCA
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Prostate cancer

Targets

Target 1
CD8
Gene ID
UniProt ID
Alternative Names
CD8A; CD8a molecule; Cluster of differentiation 8; CD8; MAL; p32; Leu2
Target 2
PSCA
Gene ID
UniProt ID
Alternative Names
PSCA; prostate stem cell antigen; PRO232

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