Recombinant Anti-CD89 x Anti-EGFR Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-CD89 and anti-EGFR parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget macrophages to tumor cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Non-small cell lung cancer (NSCLC); Solid tumors therapy.