Name: Recombinant Anti-CD89 x Anti-HIV-1 gp41 Bispecific Antibody (scFv-IgG)
SKU: BSSG-133
Rating: 5 (1 reviews)

Recombinant Anti-CD89 x Anti-HIV-1 gp41 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD89 antibody variable domain are respectively connected to the N terminus of the anti-HIV-1 gp41 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget macrophages to tumor cells. It is designed for the research of HIV-1 infection, AIDS therapy.

Datasheet INQUIRY

Specifications

Targets

CD89 & HIV-1 gp41

Type

scFv-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

HIV-1 infection, AIDS

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD89

Gene ID

2204

UniProt ID

P24071

Alternative Names

FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

Target 2

HIV-1 gp41

Gene ID

155971

UniProt ID

Q0H5Z9

Alternative Names

ENV; gp160; Envelope glycoprotein 120; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; human immunodeficiency virus type 1; human immunodeficiency virus type 1 gp120; human immunodeficiency virus type 1 glycoprotein 120; gp41; GP41; glycoprotein 41

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD89 x Anti-HIV-1 gp41 Bispecific Antibody (scFv-IgG) (CAT#: BSSG-133)

Specifications

Targets

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