Recombinant Anti-CD89 x Anti-malaria antigen Bispecific Antibody (Fab-scFv-Fc) (FABVC-134)

Recombinant Anti-CD89 x Anti-malaria antigen Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD89 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-malaria antigen to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of Malaria therapy.

Datasheet INQUIRY

Specifications

Targets

CD89 & malaria antigen

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Malaria

Targets

Target 1

CD89

Gene ID

2204

UniProt ID

P24071

Alternative Names

FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

Target 2

malaria antigen

Alternative Names

malaria antigen; parasitic protozoans

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD89 x Anti-malaria antigen Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-134)

Specifications

Targets

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