Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (Diabody-CH3) (BSDBC-135)

Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CD89 and anti-S. pneumoniae antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of S. pneumoniae infection therapy.

Datasheet INQUIRY

Specifications

Targets

CD89 & S. pneumoniae

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

S. pneumoniae infection

Targets

Target 1

CD89

Gene ID

2204

UniProt ID

P24071

Alternative Names

FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

Target 2

S. pneumoniae

Alternative Names

S. pneumoniae; Streptococcus pneumoniae; serotype of Streptococcus pneumoniae

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-135)

Specifications

Targets

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