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Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (Diabody-Fc)  (BSDBF-135)

Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CD89 and anti-S. pneumoniae antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of S. pneumoniae infection therapy.

Specifications

Targets
CD89 & S. pneumoniae
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD89
Host Animal 1
Mouse
Target 2
S. pneumoniae
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
S. pneumoniae infection

Targets

Target 1
CD89
Gene ID
UniProt ID
Alternative Names
FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
Target 2
S. pneumoniae
Alternative Names
S. pneumoniae; Streptococcus pneumoniae; serotype of Streptococcus pneumoniae

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