Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD89/anti-S. pneumoniae diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of S. pneumoniae infection therapy.