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Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-CH3)  (BSFC-135)

Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD89 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-S. pneumoniae scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of S. pneumoniae infection therapy.

Specifications

Targets
CD89 & S. pneumoniae
Type
scFv-CH3
Species Reactivity
Human
Target 1
CD89
Host Animal 1
Mouse
Target 2
S. pneumoniae
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
S. pneumoniae infection

Targets

Target 1
CD89
Gene ID
UniProt ID
Alternative Names
FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
Target 2
S. pneumoniae
Alternative Names
S. pneumoniae; Streptococcus pneumoniae; serotype of Streptococcus pneumoniae

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