Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-Fc-scFv) (BSTF-135)

Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD89 scFv is fused to the N-terminus of Fc via a hinge region while another anti-S. pneumoniae scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of S. pneumoniae infection therapy.

Datasheet INQUIRY

Specifications

Targets

CD89 & S. pneumoniae

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

S. pneumoniae infection

Targets

Target 1

CD89

Gene ID

2204

UniProt ID

P24071

Alternative Names

FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

Target 2

S. pneumoniae

Alternative Names

S. pneumoniae; Streptococcus pneumoniae; serotype of Streptococcus pneumoniae

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-135)

Specifications

Targets

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