Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-IgG) (BSSG-135)

Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD89 antibody variable domain are respectively connected to the N terminus of the anti-S. pneumoniae IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of S. pneumoniae infection therapy.

Datasheet

Specifications

Targets

CD89 & S. pneumoniae

Type

Appended IgGs

Species Reactivity

Human

Target 1

CD89

Host Animal 1

Mouse

Target 2

S. pneumoniae

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

S. pneumoniae infection

Targets

Target 1

CD89

Gene ID

2204

UniProt ID

P24071

Alternative Names

FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

Target 2

S. pneumoniae

Alternative Names

S. pneumoniae; Streptococcus pneumoniae; serotype of Streptococcus pneumoniae

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