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Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-IgG)  (BSSG-135)

Recombinant Anti-CD89 x Anti-S. pneumoniae Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD89 antibody variable domain are respectively connected to the N terminus of the anti-S. pneumoniae IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of S. pneumoniae infection therapy.

Specifications

Targets
CD89 & S. pneumoniae
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD89
Host Animal 1
Mouse
Target 2
S. pneumoniae
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
S. pneumoniae infection

Targets

Target 1
CD89
Gene ID
UniProt ID
Alternative Names
FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
Target 2
S. pneumoniae
Alternative Names
S. pneumoniae; Streptococcus pneumoniae; serotype of Streptococcus pneumoniae

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