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Recombinant Anti-CEA x Anti-DR5 Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-136)
Recombinant Anti-CEA x Anti-DR5 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CEA antibody are fused to the C terminus of an anti-DR5 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.
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