Home > Products > CEA & DR5 > Recombinant Anti-CEA x Anti-DR5 Bispecific Antibody (Miniantibody)

Recombinant Anti-CEA x Anti-DR5 Bispecific Antibody (Miniantibody)  (MNAB-136)

Recombinant Anti-CEA x Anti-DR5 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CEA antibody variable domain is linked to another scFv of an anti-DR5 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Specifications
Targets
CEA & DR5
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Mouse
Target 2
DR5
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
DR5
Gene ID
UniProt ID
Alternative Names
DR5; Death Receptor 5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; TNFRSF10B
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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