Recombinant Anti-CEA x Anti-DR5 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CEA scFv fused to N-terminus of Knob-CH3 domain and the anti-DR5 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.
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