Home > Products > CEA & DR5 > Recombinant Human Anti-CEA x Human Anti-DR5 Bispecific Antibody (scFv-CH1/CL)

Recombinant Human Anti-CEA x Human Anti-DR5 Bispecific Antibody (scFv-CH1/CL)  (BSCC-H308)

Recombinant Anti-CEA x Anti-DR5 Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-CEA antibody variable domain is fused to CH1 and the other scFv from an anti-DR5 antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Specifications
Targets
CEA & DR5
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Mouse
Target 2
DR5
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
DR5
Gene ID
UniProt ID
Alternative Names
DR5; Death Receptor 5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; TNFRSF10B
Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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