Home > Products > CEA & GD2 > Recombinant Human Anti-CEA x Human Anti-GD2 Bispecific Antibody (Diabody-Fc)

Recombinant Human Anti-CEA x Human Anti-GD2 Bispecific Antibody (Diabody-Fc)  (BSDBF-H309)

Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CEA and anti-GD2 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can bind two factors simultaneously. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Specifications

Targets
CEA & GD2
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Human
Target 2
GD2
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

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