Home > Products > CEA & GD2 > Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Fab-Fv)

Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Fab-Fv)  (FABFV-138)

Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-CEA antibody are fused with the VL and VH domains of an anti-GD2 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can bind two factors simultaneously. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Specifications

Targets
CEA & GD2
Type
Fab-Fv
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Mouse
Target 2
GD2
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

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