Recombinant Human Anti-CEA x Human Anti-GD2 Bispecific Antibody (Tandem scFv-Fc) (BSFVF-H309)

Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-CEA/GD2 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can bind two factors simultaneously. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

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Specifications

Targets

CEA & GD2

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CEA x Human Anti-GD2 Bispecific Antibody (Tandem scFv-Fc) (CAT#: BSFVF-H309)

Specifications

Targets

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