Recombinant Anti-CEA x Anti-nido-carboranes Bispecific Antibody (scFv-IgG) (BSSG-141)

Recombinant Anti-CEA x Anti-nido-carboranes Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CEA antibody variable domain are respectively connected to the N terminus of the anti-nido-carboranes IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

CEA & nido-carboranes

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Target 2

nido-carboranes

Alternative Names

nido-carboranes

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CEA x Anti-nido-carboranes Bispecific Antibody (scFv-IgG) (CAT#: BSSG-141)

Specifications

Targets

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