Name: Recombinant Anti-CEA x Anti-nido-Carboranes Bispecific Antibody (scFv4-Ig)
SKU: FVTIG-141
Rating: 5 (1 reviews)

Recombinant Anti-CEA x Anti-nido-carboranes Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CEA scFv is fused to the CH1 domain of a heavy chain and another anti-nido-carboranes scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

CEA & nido-Carboranes

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Target 2

nido-Carboranes

Alternative Names

nido-carboranes

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CEA x Anti-nido-Carboranes Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-141)

Specifications

Targets

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