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Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (Fv-IgG) (CAT#: BSDG-142)
Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-CEA IgG with similar domains from an anti-TNFα antibody via short peptide linkers, or vice versa. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.
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