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Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-142)
Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CEA antibody are fused to the C terminus of an anti-TNFα IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.
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