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Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (Minibody) (CAT#: MiniB-142)
Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (Minibody) is designed to be expressed as the anti-CEA scFv fused to N-terminus of Knob-CH3 domain and the anti-TNFα scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.
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