Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CEA/anti-TNFα diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.
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