Home > Products > CEA & TNFα > Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (scDiabody-Fc)

Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (scDiabody-Fc)  (SCDBF-142)

Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (scDiabody-Fc) is a fusion protein of two scDiabodies with an Fc region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CEA/anti-TNFα diabody. The scDiabody with two specificities is further fused to the Fc domain to form BsAb with 2+2 antigen-binding valency. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Specifications
Targets
CEA & TNFα
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Mouse
Target 2
TNFα
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
TNFα
Gene ID
UniProt ID
Alternative Names
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
45-1 Ramsey Road, Shirley, NY 11967, USA
Email:
Fax: 1-631-207-8356
Or Call
Tel: 1-631-381-2994
Related products of "CEA & TNFα"
45-1 Ramsey Road, Shirley, NY 11967, USA 1-631-381-2994 1-631-207-8356
24x7 CUSTOMER SERVICE
Easy access to products and services you need from our library via
powerful searching tools
© 2007 - 2020 Creative-Biolabs All Rights Reserved.
Distributors
To view the contact information for a specific location,
select your country or region: