Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (scFv-Fc)  (BSCFV-H311)

Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CEA specificity or anti-TNFα specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

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