Recombinant Human Anti-CEA x Human Anti-TNFα Bispecific Antibody (scFv4-Ig)  (FVTIG-H311)

Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CEA scFv is fused to the CH1 domain of a heavy chain and another anti-TNFα scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

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